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AoU Research Priorities Use Cases

What treatments are effective in reducing anxiety and increasing stress tolerance in high-functioning, children with autism

A cohort study of pre-teens with high functioning autism, formerly Aspergers, would collect data about pharmacological and behavioral therapies tried and obtain dose and duration of treatments. Survey data from parents would measure functioning and stress tolerance at age 10, 13 and 18.

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AoU Research Priorities Use Cases

What is the genetic architecture of neurodevelopmental problems and how does it relate to health disparities?

From a diverse sample of children in both clinical and non-clinical settings, investigate genetic contributions to a wide range of neurodevelopmental problems (NPs). Individual-variant and polygenic approaches can advance our understanding of the genetic overlap between, and specificity in, different types of NPs. In a large and diverse sample that includes different racial/ethnic and socioeconomic groups, these techniques... more »

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33 votes
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(@nichd.allofus)

AoU Research Priorities Use Cases

What is the genetic architecture of neurodevelopmental problems and how does it relate to health disparities?

From a diverse sample of children in both clinical and non-clinical settings, investigate genetic contributions to a wide range of neurodevelopmental problems (NPs). Individual-variant and polygenic approaches can advance our understanding of the genetic overlap between, and specificity in, different types of NPs. In a large and diverse sample that includes different racial/ethnic and socioeconomic groups, these techniques... more »

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33 votes
Ideate