(@mbl2018)

AoU Research Priorities Use Cases

How do our mindsets about diet, exercise, and stress influence health behaviors and health outcomes?

Research has shown that benefits of health behaviors such as diet, exercise, and stress depend not just on the behaviors themselves but on the mindsets people have about those behaviors (Crum, Achor & Salovey, 2013; Zahrt & Crum 2017; Turnwald, Boles & Crum 2017); however, large-scale databases have not yet included measures of mindset. The goal of this study is to use validated measures of exercise, stress and diet mindsets... more »

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(@ataylor)

AoU Research Priorities Use Cases

What are the future outcomes for people who present with REM sleep behavior disorder (physically acting out dreams while asleep)

REM sleep behaviour (RBD) can precede subsequent Lewy body disease by many years/decades. Thus RBD could be a potent prodromal biomarker of future disease and allow for identification of an ideal target population for disease modifying treatment. In depth assessment of sleep behaviours in midlife as measured using participant survey complimented by wearable devices technology could provide unparalleled information in... more »

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16 votes
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(@chouws)

AoU Research Priorities Use Cases

How does participants’ health literacy (HL) level compare to national estimates and what is the role of HL in health outcomes?

Populations of limited health literacy have traditionally been underrepresented in genomic/genetic studies. We propose that All of Us participants complete brief baseline HL survey items as part of the Participant-Provided Information (PPI; The Basics). HL measures can be analyzed in comparison with national estimates and in conjunction with other All of Us measures (e.g., uptake on genetic testing, behavioral outcomes,... more »

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12 votes
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(@chouws)

AoU Research Priorities Use Cases

How does participants’ health literacy (HL) level compare to national estimates and what is the role of HL in health outcomes?

Populations of limited health literacy have traditionally been underrepresented in genomic/genetic studies. We propose that All of Us participants complete brief baseline HL survey items as part of the Participant-Provided Information (PPI; The Basics). HL measures can be analyzed in comparison with national estimates and in conjunction with other All of Us measures (e.g., uptake on genetic testing, behavioral outcomes,... more »

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12 votes
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(@jenna.norton)

AoU Research Priorities Use Cases

What characteristics are associated with maintenance of increased water intake in persons with urinary stone disease?

Increased water intake reduces stone recurrence, but maintaining increased intake is challenging. Via the EHR and qualitative/quantitative methods, we will identify person and intervention characteristics associated with maintenance of increased intake to determine factors that facilitate intervention success and/or enable targeted interventions. Findings may provide insights into strategies for maintenance of behavior... more »

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11 votes
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(@jenna.norton)

AoU Research Priorities Use Cases

What characteristics are associated with maintenance of increased water intake in persons with urinary stone disease?

Increased water intake reduces stone recurrence, but maintaining increased intake is challenging. Via the EHR and qualitative/quantitative methods, we will identify person and intervention characteristics associated with maintenance of increased intake to determine factors that facilitate intervention success and/or enable targeted interventions. Findings may provide insights into strategies for maintenance of behavior... more »

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11 votes
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(@bcuthber)

AoU Research Priorities Use Cases

How can we best determine and validate domains of behavioral functioning to achieve precision assessments for mental disorders?

Assessment and treatment of mental disorders increasingly focus on neurocircuit-based abnormalities in functional domains such as emotion and cognition. There is a need for computational modeling to define and validate critical dimensions of psychopathology, using optimal behavioral tasks and patient-reported outcomes to develop refined diagnoses and outcome measures. Large samples are required for modeling analyses that... more »

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17 votes
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