Showing 5 ideas for tag "bladder"
(@diane.newman) kudos icon +

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What factors predict response to lifestyle modification & bladder training in adults with symptoms of overactive bladder (OAB)?

Lifestyle (eg, diet) modification & bladder retraining (LMBR) are effective for many but not all persons with OAB symptoms (urinary urgency, frequency + incontinence). We will identify determinants of successful LMBR in a prospective cohort of adults with OAB symptoms treated with LMBR by comparing hypothesized moderators of LMBR spanning medical and social ecological models (eg, self-efficacy, race, occupation, SES,... more »

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3 votes
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(@hhenrylai) kudos icon +

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What are the biological, environmental, and behavioral factors associated with the longitudinal trends of interstitial cystitis?

Interstitial cystitis (IC) is defined by the hallmark symptoms of chronic pelvic or bladder pain, often accompanied by urgency or frequency of urination. Using data from over 1 million men and women, we will examine the natural history and longitudinal trends of IC symptoms over 10 years in a diverse population that are traditionally underrepresented in IC research. We will also examine the biological, environmental,... more »

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6 votes
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(@hhenrylai) kudos icon +

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What are the biological, behavioral and metabolic factors that predict response vs non-response to overactive bladder treatment?

One out of 6 adults in the US (33 millions) and one out of 10 worldwide (546 millions) are affected by overactive bladder (OAB). Despite the high economic cost ($82 billions by 2020), treatment response to OAB remains suboptimal. Using data from over 1 million men and women, we will identify biological (eg, genomics, ethnicity, medical history), behavioral (lifestyle), and metabolic factors (eg, metabolic syndrome, obesity)... more »

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8 votes
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(@arianasmith) kudos icon +

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In Overactive Bladder does pharmacogenomics influence individual response to antimuscarinic and beta-agonist bladder medication?

Overactive bladder is highly prevalent with significant impact on quality of life. Medications are utilized despite variable efficacy, high side effect burden, and poor persistence on therapy. This study will identify an overactive bladder cohort who have been prescribed antimuscarinic or beta-agonist medication to relieve symptoms. We hypothesize relief of symptoms will be based on the individuals pharmacogenomics. Personalized... more »

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28 votes
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(@jenna.norton) kudos icon +

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Does surgery to relieve obstruction from benign prostate enlargement (BPE) improve metabolic risk profile (MRP)?

Frequent and urgent urination secondary to obstruction from prostate enlargement may reduce physical activity and adherence to diuretics, thereby increasing metabolic risk profile. This study will identify a prospective subcohort of men with incident surgery to relieve bladder outlet obstruction (BOO). We hypothesize relief of LUTS will decrease need to urinate, increase level of physical activity, and reduce MRP. Patient... more »

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17 votes
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