Adverse childhood experiences (ACE) can be retrospectively assessed in adults, ideally before the onset of the diseases under study. There are existing ACE instruments, or attempts to refine these instruments could be undertaken within All of Us.
Children often present differently with Sjögren's when compared with adults leading to delayed diagnosis and treatment. Additionally, awareness of Sjögren's in children among clinicians is low, which may further delay diagnosis and treatment. This study would focus on learning how to better identify, manage, and treat Sjögren's in this special population and how disease expression and pathways differ in children compared... more »