Congenital cytomegalovirus (CMV) infection is the most common congenital infection, and a common cause of neurodevelopmental disabilities, growth failure, hearing loss and vision loss. Prevention of congenital CMV by vaccination was deemed a national priority for the 21st century by the Institute of Medicine in 2000. Information on the health economics of this common congenital infection is necessary to drive prevention... more »
Anosmia, the loss of smell, affects approximately 5% of the population and can blight the lives of sufferers. The consequences to well being of those with this condition can be severe and include depression, anxiety, aggression, feelings of isolation as well as weight gain/weight loss. Within this group are people with parosmia, a condition where odors are so distorted that food becomes a nauseating ordeal. We need more... more »
A good estimate could be based on a simple survey of health care providers (ENT or internist) as to the frequency of patients who exhibit this important disability. Depending on the results, more resources might be devoted to finding causes and ultimately treatments.
I am a lay person and I cannot provide detail on study design. However, I am aware that there are millions of individuals world-wide who suffer from loss of smell (anosmia) and who feel socially isolated and fearful of dangers that the olfactory system helps to warn against. In addition, many people who are anosmic do not enjoy eating and are therefore not necessarily getting a nutritionally balanced diet. This could... more »