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AoU Research Priorities Use Cases

How do genomic, biological, environmental and societal factors combine to contribute to disease risk?

Complex diseases are a result of a complex interplay of genetic, environmental, host and societal factors operating over a prolonged time. Many factors associated with disease onset or progression have been elucidated using a silo-ed approach which fails to adequately assess interplay between factors. Longitudinal measures and more sophisticated analytical methods are needed to support comprehensive (e.g. systems or computational... more »

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AoU Research Priorities Use Cases

What is the impact of time-varying, place-based social determinants of health measures on physical and mental health

To answer important physical and mental health questions we need to understand the trajectory of the individuals and the trajectories of the places they have lived (residential histories). If exposure equals space x time (over the life courses) we need data on the timing, sequence and duration of residence in specific contexts (places). How we define/measure place is important for (retro)prospective work and will enables... more »

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