(@cavin.ward)

AoU Research Priorities Use Cases

What lifestyle factors, e.g. diet, physical activity, are associated with protection against environmental pollutants?

Most research is devoted understanding factors which increase disease risk. Here we specifically seek to find individuals who are healthy despite exposure to high levels of environmental pollutants, e.g. living in areas with elevated air pollution, and examine the lifestyle factors which may be protective. Protective lifestyle factors may be modifiable by the individual and may represent a means to improve environmental... more »

Voting

16 votes
Ideate
(@tyrolk)

AoU Research Priorities Use Cases

How Well Do Recipients of Weight-Loss Surgery (WLS) Believe They Were Informed of the Risks and Restrictions The Surgery Poses

WLS poses a variety of risks as well as a very specific set of restrictions: initially a highly restricted diet that relaxes over time. These risks/restrictions carry with them an emotional & sociocultural cost that is difficult to convey. I propose juxtaposing provider expectations of patient knowledge about risks and restrictions w/ patient reflections on the nuanced meaning of same. What do patients wish they'd known... more »

Voting

4 votes
Ideate
(@tyrolk)

AoU Research Priorities Use Cases

How Well Do Recipients of Weight-Loss Surgery (WLS) Believe They Were Informed of the Risks and Restrictions The Surgery Poses

WLS poses a variety of risks as well as a very specific set of restrictions: initially a highly restricted diet that relaxes over time. These risks/restrictions carry with them an emotional & sociocultural cost that is difficult to convey. I propose juxtaposing provider expectations of patient knowledge about risks and restrictions w/ patient reflections on the nuanced meaning of same. What do patients wish they'd known... more »

Voting

4 votes
Ideate
(@zoradjuric)

AoU Research Priorities Use Cases

Does weight gain negate the beneficial effects of eating healthy foods?

Adult weight gain and obesity increase risks of chronic diseases. The effects of a positive energy balance could outweigh any beneficial effects of foods associated with reduced health risks such as vegetables, whole grains and omega-3 fatty acids. In subsets of adults who are either gaining weight or maintaining weight over time, does the impact of diet quality on health risks differ? Diet could be quantified by various... more »

Voting

10 votes
Ideate
(@mpwhitmire)

AoU Research Priorities Use Cases

What social determinants & health/functional factors increase the risk of malnutrition for older adults living in the community?

It is important that the All of Us database includes a range of nutrition-related measures which are used to help identify malnutrition risk. Additional measures of malnutrition-related characteristics are important for malnutrition diagnosis. Validated screening tools such as the Malnutrition Screening Tool (MST) could be used regularly to collect this data, as well as linked surveys to capture demographic information... more »

Voting

75 votes
Ideate
(@mpwhitmire)

AoU Research Priorities Use Cases

What is the malnutrition risk of older adults living in the community?

It is important that the All of Us database includes a range of nutrition-related measures--not just diet and BMI--but other parameters such as weight history and appetite history which are used to help identify malnutrition risk. Additional measures of malnutrition-related characteristics are important for malnutrition diagnosis. Validated screening tools such as the Malnutrition Screening Tool (MST) could be used regularly... more »

Voting

13 votes
Ideate
(@ziggeyz13)

AoU Research Priorities Use Cases

Conduct research to determine if chronic conditions such as diabetes can be improved through non-medication methods

There is a lot of controversy on whether a disease can be treated based primarily on a change of diet. With this study I would test the theory with participants from various groups to determine if the condition could be improved through diet and also determine is medication is needed for improvement

Voting

15 votes
Ideate
(@dgold217)

AoU Research Priorities Use Cases

Does a diet high in carbohydrates contribute to obesity and diabetes?

The typical American diet, defined by high quantities of processed carbohydrates, and not high fat, has led to an obesity epidemic in the United States and well as skyrocketing diabetes. I propose to analyze the number of carbohydrate grams consumed in two test groups, the typical American diet (control) and test subjects who identify themselves as “keto” or “low carb” to confirm that a low carbohydrate diet is the key... more »

Voting

16 votes
Ideate
(@bcarverme)

AoU Research Priorities Use Cases

Investigate the role of environmental and dietary factors in the incidence of chronic pain

Investigate the correlation between the incidence of reported pain and various social and biological characteristics. Investigate the correlation between the incidence of reported pain and dietary factors including foods, food additives such as dyes, preservatives and other additives. Investigate the correlation between the incidence of reported pain and environmental exposures including pollution, pesticides and the... more »

Voting

23 votes
Ideate
(@drirene)

AoU Research Priorities Use Cases

Could the Precision Medicine Initiative Reduce Social Inequality?

The proposed study would identify microbial communities and metabolic profiles associated with stigmatized conditions such as idiopathic malodor or mental health. Working with systemic malodor/PATM community provides unprecedented opportunities to explore biomarkers of depression, social stress, diabetes, inflammatory diseases, dental, cardiovascular, and digestive health, exposure to antibiotics, lifestyle & dietary... more »

Voting

219 votes
Ideate
(@cpeterso)

AoU Research Priorities Use Cases

How do different food groups affect health?

Administer food diaries and assess the impact of food groups/categories, such as fruits, root vegetables, green leafy vegetables, all other vegetables, low-fat dairy, full fat dairy, fish, white meat, red meat, processed meat, nuts & seeds, beans/legumes, whole grains made from flour (pasta, bread, pastries), intact whole grains (i.e., whole grain products not made from flour), refined grains, refined sugar, oils, etc.... more »

Voting

24 votes
Ideate
(@karen.montefiori)

AoU Research Priorities Use Cases

How does a life-long adherence to healthy life style habits affect the aging process?

Goal: Show that a strict, and life-long adherence to a healthy life style retards the aging process, enables you to avoid many common diseases, and allows you to greatly reduce healthcare costs. Method: Invite participants from all over the world to commit to following a healthy life style regimen throughout life. Expected outcomes: Participates age more slowly, have fewer chronic diseases, and spend less on health... more »

Voting

33 votes
Ideate
(@nichd.allofus)

AoU Research Priorities Use Cases

What microbiome characteristics of children exposed to antibiotics and different diets influence long-term health outcomes?

Follow a subsample of all infants and children (< 3 years of age) throughout childhood to obtain the following serial assessments: blood tests, medication history, neonatal, infant and childhood health outcomes; physical measurements and laboratory microbiologic evaluations of oral, skin and vaginal specimens. Assessments and measures would be used along with health outcomes to determine associations and develop predictive... more »

Voting

153 votes
Ideate
(@nichd.allofus)

AoU Research Priorities Use Cases

What microbiome characteristics of children exposed to antibiotics and different diets influence long-term health outcomes?

Follow a subsample of all infants and children (< 3 years of age) throughout childhood to obtain the following serial assessments: blood tests, medication history, neonatal, infant and childhood health outcomes; physical measurements and laboratory microbiologic evaluations of oral, skin and vaginal specimens. Assessments and measures would be used along with health outcomes to determine associations and develop predictive... more »

Voting

153 votes
Ideate
(@nichd.allofus)

AoU Research Priorities Use Cases

What characteristics distinguish a healthy maternal pregnancy-microbiome from one that experienced microbial perturbations?

This study will focus on a subsample of all pregnant women and follow them throughout pregnancy to obtain serial assessments and measurements, including laboratory microbiologic evaluation testing of oral, skin and vaginal specimens. Follow-up would end at delivery of the infant; serial pregnancies would be eligible to re-enroll. Assessments and measures would be used along with health outcomes to determine associations... more »

Voting

43 votes
Ideate