(@abaccarelli)

AoU Research Priorities Use Cases

Does the human epigenome reflect exposure to environmental chemicals?

The human epigenome is altered by environmental pollutants, including particulate air pollution, bisphenol A, phthalates, metals, pesticides, dioxin-like compounds, and persistent organic pollutants. All of us will be uniquely positioned to link exposure to environmental chemicals with alterations in the human epigenome. This will require refined measures of environmental exposure that—if measured in All of us—will cause... more »

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(@abaccarelli)

AoU Research Priorities Use Cases

Does the human epigenome reflect exposure to environmental chemicals?

The human epigenome is altered by environmental pollutants, including particulate air pollution, bisphenol A, phthalates, metals, pesticides, dioxin-like compounds, and persistent organic pollutants. All of us will be uniquely positioned to link exposure to environmental chemicals with alterations in the human epigenome. This will require refined measures of environmental exposure that—if measured in All of us—will cause... more »

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4 votes
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(@richard.becker.uc.edu)

AoU Research Priorities Use Cases

primordial cardiology and the unified theory of atherosclerosis

Cardiovascular diseases, collectively the most common cause of death, disability and healthcare expenditures in North America and Europe are recognized as complex genetic and environmental phenotypes. While they can and traditionally have been studied individually, we believe that there are unified mediators of vascular injury and dysregulation. A “unified coronary arterial atherosclerosis theory” would better explain... more »

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