(@nichd.allofus)

AoU Research Priorities Use Cases

What is the effect of the individual’s family and community network on health status and health behaviors?

Focusing on the entire cohort, this study seeks to define inter-relationship linkages between the person (“ego”) and other associated participants (“alters”). Previous studies identified linkages through the specification of a family roster and alternate points of contact in the consent process. The relationship data produced would be available for network analysis to determine the impact of the social network on health ...more »

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23 votes
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(@landim)

AoU Research Priorities Use Cases

What is the etiology of lung cancer in never smokers?

Incidence and mortality rates of lung cancer in never smokers are high. Known risk factors only account for a small fraction of the cases. Methods to identify novel exogenous and endogenous processes of lung carcinogenesis: integrating genomics analyses of somatic mutational signatures + epidemiological and clinical data of risk factors and personal and family medical history + geocoded measures of residential exposures ...more »

Voting

8 votes
Ideate
(@landim)

AoU Research Priorities Use Cases

What is the etiology of lung cancer in never smokers?

Incidence and mortality rates of lung cancer in never smokers are high. Known risk factors only account for a small fraction of the cases. Methods to identify novel exogenous and endogenous processes of lung carcinogenesis: integrating genomics analyses of somatic mutational signatures + epidemiological and clinical data of risk factors and personal and family medical history + geocoded measures of residential exposures ...more »

Voting

8 votes
Ideate
(@on9cloud)

AoU Research Priorities Use Cases

What factors determine your willingness to share your Electronic Health Record?

I propose to study what are factors (demography, disease history, symptoms, genetics, environment) play a role in deciding to share your Electronic Health Record (EHR).

Using EHR for research leads to much faster acquisition of data and AllOfUs offers a unique opportunity to study this in further. (similarly for electronic dental record)

Voting

17 votes
Ideate
(@nichd.allofus)

AoU Research Priorities Use Cases

Can Electronic Health Records (EHRs) be effectively utilized to facilitate clinical trials in pediatrics?

Use of EHRs in interventional trials is challenging due to lack of standardization and harmonization. There is a need to incorporate common data elements (developmental data, symptoms), establish linkages (event flags; real-time links for diagnosis, treatment and adherence), enhance interoperability across vendor systems, standardize adverse event capture, develop identification for phenotypes or rare diseases, and streamline ...more »

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114 votes
Ideate