(@tlcfoundationforbfrbs)

AoU Research Priorities Use Cases

What are the phenotypic and genetic factors associated with behavioral addictions?

Behavioral addictions (e.g., hair pulling, skin picking, gambling, internet addiction, etc.) are common chronic problems involving shared neural mechanisms (e.g., dopamine dysfunction) and repeated urges to engage in harmful acts. To enhance knowledge of underlying mechanisms and inform treatment development we will identify phenotypic (i.e., comorbidity, affect, impulsivity, reward, sensory measures) subtypes using latent ...more »

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(@nichd.allofus)

AoU Research Priorities Use Cases

How do genetic factors of ADHD influence treatment strategies? Can they affect success of treatment or the choice of therapy?

Screen school-age children for ADHD by testing, if feasible, or by electronic health record search. Perform WGS on children as the preferred strategy to identify new genetic associations and confirm previously reported genetic associations. If WGS is not possible, develop a marker panel and test children who have ADHD for known or suspected genetic factors. Follow children by periodic medical evaluations and school performance ...more »

Voting

94 votes
Ideate
(@nichd.allofus)

AoU Research Priorities Use Cases

How do genetic factors of ADHD influence treatment strategies? Can they affect success of treatment or the choice of therapy?

Screen school-age children for ADHD by testing, if feasible, or by electronic health record search. Perform WGS on children as the preferred strategy to identify new genetic associations and confirm previously reported genetic associations. If WGS is not possible, develop a marker panel and test children who have ADHD for known or suspected genetic factors. Follow children by periodic medical evaluations and school performance ...more »

Voting

94 votes
Ideate