Chronic stress has significant suppressive impact on the immune system and would influence the risk of infection-associated cancers if high risk infections are allowed to persist. In general populations and healthy adult populations, this question has not been addressed. It would involve serial measurement of oral or anogenital human papillomavirus, or even helicobacter pylori.
Precision microbiome engineering could be applied to vaccine delivery, immunology, drug-resistant infections, and post-surgical infections. Specific research questions re pathogenesis and treatment: - What aspects of the indigenous microbiota mediate colonization resistance against C. difficile, as well as other multi-drug resistant organisms such as carbapenamase-producing gram negative bacteria and vancomycin resistant... more »