(@lisa.signorello)

AoU Research Priorities Use Cases

How does chronic stress influence the persistence of oncogenic viruses or bacteria in otherwise healthy adults?

Chronic stress has significant suppressive impact on the immune system and would influence the risk of infection-associated cancers if high risk infections are allowed to persist. In general populations and healthy adult populations, this question has not been addressed. It would involve serial measurement of oral or anogenital human papillomavirus, or even helicobacter pylori.

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2 votes
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(@lisa.signorello)

AoU Research Priorities Use Cases

How does chronic stress influence the persistence of oncogenic viruses or bacteria in otherwise healthy adults?

Chronic stress has significant suppressive impact on the immune system and would influence the risk of infection-associated cancers if high risk infections are allowed to persist. In general populations and healthy adult populations, this question has not been addressed. It would involve serial measurement of oral or anogenital human papillomavirus, or even helicobacter pylori.

Voting

2 votes
Ideate
(@idsociety)

AoU Research Priorities Use Cases

Using human microbiome data to improve pathogenesis and treatment of infectious diseases

Precision microbiome engineering could be applied to vaccine delivery, immunology, drug-resistant infections, and post-surgical infections. Specific research questions re pathogenesis and treatment: - What aspects of the indigenous microbiota mediate colonization resistance against C. difficile, as well as other multi-drug resistant organisms such as carbapenamase-producing gram negative bacteria and vancomycin resistant... more »

Voting

31 votes
Ideate
(@idsociety)

AoU Research Priorities Use Cases

Using human microbiome data to improve pathogenesis and treatment of infectious diseases

Precision microbiome engineering could be applied to vaccine delivery, immunology, drug-resistant infections, and post-surgical infections. Specific research questions re pathogenesis and treatment: - What aspects of the indigenous microbiota mediate colonization resistance against C. difficile, as well as other multi-drug resistant organisms such as carbapenamase-producing gram negative bacteria and vancomycin resistant... more »

Voting

31 votes
Ideate