Urinary stone disease is burdensome and costly, and frequently recurs. Via the EHR and qualitative/quantitative methods, we will identify person and intervention characteristics associated with urinary stone recurrence. Factors associated with recurrence may provide potential treatment targets for preventing stone recurrence.
Showing 5 ideas for tag "kidney"
Glomerular disorders represent the third-most common cause of end-stage kidney disease after diabetes and hypertension. Well-designed and adequately powered clinical, genetic and environmental exposure studies are missing for most glomerular disease types. Using genetic and environmental variables combined with kidney-related structured electronic health record phenotype data captured by All-of-US, we aim to identify... more »
This would be a mixed methods study. The qualitative section would involve interviews to ascertain gaps in in chronic kidney disease communication (likely risk assessment in CKD progression, information about dialysis options, mental health, advance care planning). This would be followed by surveys of patient-reported measures of communication, such as CAT (Communication Assessment Tool; https://www.ncbi.nlm.nih.gov/pubmed/17574367).... more »
Increased water intake reduces stone recurrence, but maintaining increased intake is challenging. Via the EHR and qualitative/quantitative methods, we will identify person and intervention characteristics associated with maintenance of increased intake to determine factors that facilitate intervention success and/or enable targeted interventions. Findings may provide insights into strategies for maintenance of behavior... more »
I have a cousin who is undergoing chemotherapy for renal medullary carcinoma, a cancer specific to patients with sickle cell. Aside from the fact that we need to discover a means of eradicating sickle cell from our planet, will the All of Us program be used to further research into the development of better treatment options for patients who develop this cancer? The pool of candidates is very small due to rarity of the... more »