Adverse childhood experiences (ACE) can be retrospectively assessed in adults, ideally before the onset of the diseases under study. There are existing ACE instruments, or attempts to refine these instruments could be undertaken within All of Us.
Too many people have comorbid brain disorders. Not enough is known each disease independently, what causes them and what, if anything, contributes to resilience in the rest of us who do not suffer from them. Research on familial links, people with similar comorbid brain disorders, genetics that play into who gets these diseases and how individuals react uniquely to medications can all lead us to a better understanding,... more »