AoU Research Priorities Use Cases

Can metabolite profiles improve disease prediction and management?

The window of opportunity for disease prevention in at-risk individuals may be before symptoms occur and blood/urine chemistries indicate a problem. Considering that one’s metabolome reflects both genetic and environmental influences, could metabolite profiles be explored in the All of Us biospecimens and assessed as diagnostic tools?

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AoU Research Priorities Use Cases

Could the Precision Medicine Initiative Reduce Social Inequality?

The proposed study would identify microbial communities and metabolic profiles associated with stigmatized conditions such as idiopathic malodor or mental health. Working with systemic malodor/PATM community provides unprecedented opportunities to explore biomarkers of depression, social stress, diabetes, inflammatory diseases, dental, cardiovascular, and digestive health, exposure to antibiotics, lifestyle & dietary ...more »

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