Showing 2 ideas for tag "neurology"
(@alexandra.boukhvalova)

AoU Research Priorities Use Cases

Differentiating healthy neurological aging from incipient nervous system dysfunction using smartphone apps.

Neurons are mostly non-renewing cells and neurodegenerative diseases are often diagnosed after many already died. This severely limits therapeutic efficacy. We propose accurate, convenient measures of broad neurological functions using developed smartphone apps to test whether derived subject-specific progression slopes can differentiate healthy aging from incipient neurological dysfunction. Such analysis may eventually... more »

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(@lyn.jakeman)

AoU Research Priorities Use Cases

What are the risk factors for comorbid health outcomes in persons with immobility caused by neurological injury or disease?

This would focus on incidence of health problems in the entire cohort to ask if loss of mobility or neurological impairment are separate risk factors. Demographic and pre-enrollment ICD codes will be obtained with the All of Us Core dataset. Volunteers will be followed for 5 years with annual PPI, physical exams, and blood draws. ICD codes will be obtained at any clinical encounters. Principle component analysis will... more »

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