(@ataylor)

AoU Research Priorities Use Cases

What are the future neurodegenerative outcomes for people who develop hyposmia, anosmia or chronic constipation?

These are frequent antecedents in neurodegenerative disease. They may, in themselves, be early biomarkers and or demarcate a peripheral origin for the disease. However their onset is not well understood and they are not specific to neurodegenerative diseases. Understanding their natural history, and co-association with other midlife/old age symptoms coupled with omic data may help understand the role of these symptoms... more »

Voting

25 votes
Ideate
(@sandship)

AoU Research Priorities Use Cases

Can methods be developed to help those with sudden onset anosmia (due to head injury or illness) regain their sense of smell?

The goals of anosmia research should be to help those who have suddenly lost their sense of smell to regain it. Scientists need to know more about olfactory nerves, their connections, their regeneration, how nerves can be rerouted, etc.

Voting

36 votes
Ideate
(@chriskelly151)

AoU Research Priorities Use Cases

How can you help people who have anosmia?

Anosmia, the loss of smell, affects approximately 5% of the population and can blight the lives of sufferers. The consequences to well being of those with this condition can be severe and include depression, anxiety, aggression, feelings of isolation as well as weight gain/weight loss. Within this group are people with parosmia, a condition where odors are so distorted that food becomes a nauseating ordeal. We need more... more »

Voting

58 votes
Ideate
(@chriskelly151)

AoU Research Priorities Use Cases

How can you help people who have anosmia?

Anosmia, the loss of smell, affects approximately 5% of the population and can blight the lives of sufferers. The consequences to well being of those with this condition can be severe and include depression, anxiety, aggression, feelings of isolation as well as weight gain/weight loss. Within this group are people with parosmia, a condition where odors are so distorted that food becomes a nauseating ordeal. We need more... more »

Voting

58 votes
Ideate

AoU Research Priorities Use Cases

Identify treatments for the loss of smell (anosmia)

I am a lay person and I cannot provide detail on study design. However, I am aware that there are millions of individuals world-wide who suffer from loss of smell (anosmia) and who feel socially isolated and fearful of dangers that the olfactory system helps to warn against. In addition, many people who are anosmic do not enjoy eating and are therefore not necessarily getting a nutritionally balanced diet. This could... more »

Voting

56 votes
Ideate
(@jodyetheloner)

AoU Research Priorities Use Cases

Can you find a cure for tmau ( how to fix the FMO3 enzyme in our digestive system)

I have no clue how I would study it to be completely honest... But I have horrible body odor and terrible bad breath because of Trimethylaminuria (tmau). It is caused by a deficiency of flavin monooxygenase 3 (FMO3) secondary to mutations in the FMO3 gene. Please help me and others with this problem.

Voting

10 votes
Ideate
(@drirene)

AoU Research Priorities Use Cases

Could the Precision Medicine Initiative Reduce Social Inequality?

The proposed study would identify microbial communities and metabolic profiles associated with stigmatized conditions such as idiopathic malodor or mental health. Working with systemic malodor/PATM community provides unprecedented opportunities to explore biomarkers of depression, social stress, diabetes, inflammatory diseases, dental, cardiovascular, and digestive health, exposure to antibiotics, lifestyle & dietary... more »

Voting

219 votes
Ideate