Showing 4 ideas for tag "parkinson’s"
(@svogelstein)

AoU Research Priorities Use Cases

What is the long-term impact of consumption of organic foods on health outcomes?

Organic foods are thought to be healthier than conventional foods because of the limited exposure to pesticides and other chemicals. Few studies have examined the long-term health effects of organic foods. By collecting information on organic food consumption and comparing those who tend to consume more organic foods (e.g., organic fruits/veg) to those who consume less, we could evaluate the impact of organic food consumption... more »

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11 votes
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(@visarb)

AoU Research Priorities Use Cases

Can measures of speech and language be pre-clinical predictors of neurological disease?

Complex brain networks are responsible for translating thoughts and ideas into sequences of movements that produce the sounds of speech. Any disturbance in these networks can lead to changes in how we speak and what we say. Evidence shows that subtle changes in speech are early harbingers of neurological disease. We propose to use the AoU platform to validate this hypothesis on a large scale and to develop AI tools for... more »

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2 votes
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(@tanejagi)

AoU Research Priorities Use Cases

How does exposure to pesticides across the lifespan impact ones risk of Parkinson's disease?

Existing studies on a small scale have linked some pesticide exposure to neurologic outcomes. To investigate this on a national scale we propose collection of occupational history on all participants. Of those who worked or lived on a farm for more than one year we would follow up with a detailed questionnaire on exposures, such as pesticides and detailed use of personal protective equipment. Follow up on a control... more »

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9 votes
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(@lyn.jakeman)

AoU Research Priorities Use Cases

What are the risk factors for comorbid health outcomes in persons with immobility caused by neurological injury or disease?

This would focus on incidence of health problems in the entire cohort to ask if loss of mobility or neurological impairment are separate risk factors. Demographic and pre-enrollment ICD codes will be obtained with the All of Us Core dataset. Volunteers will be followed for 5 years with annual PPI, physical exams, and blood draws. ICD codes will be obtained at any clinical encounters. Principle component analysis will... more »

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7 votes
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