Prostate cancer has long been suspected to include an infectious etiology, although no agent has been identified. It is possible that one specific virus or bacterium is not significant, but rather the characteristics of the entire microbiota to which the prostate is exposed (e.g., the abundance and diversity of all microorganisms). This may be capturable by examining the seminal fluid microbiome.
Both Genital HSV 2 infection and prostate cancer are prevalent diagnoses.
The proposed study would answer the question if HSV genital infection in males increase prostate cancer