(@eofili)

AoU Research Priorities Use Cases

What is the relative influence of race/ethnicity and geography(zip code) in chronic disease causation?

Data suggest that place of birth is important in chronic disease causation even after people move to new locations. Similarly data abound regarding environmental exposure and chronic diseases.

Understanding gene-environment interactions in the context of race/ethnicity is important for chronic disease causation and prevention.

This study could use zip code level data to stratify risk and track interventions

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2 votes
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(@samfriedman)

AoU Research Priorities Use Cases

How do metropolitan-level factors, including residential segregation, shape pediatric and/or adult asthma?

The prevalence of asthma is on the rise and is high for racial minorities. No attention has been paid to the impact of the variation in metropolitan-level characteristics on asthma largely because of limited metropolitan variation in available data. Metropolitan-level residential segregation affects minority housing, and housing conditions are an important determinant of asthma. The All of Us project should collect asthma... more »

Voting

6 votes
Ideate
(@samfriedman)

AoU Research Priorities Use Cases

How do metropolitan-level factors, including residential segregation, shape pediatric and/or adult asthma?

The prevalence of asthma is on the rise and is high for racial minorities. No attention has been paid to the impact of the variation in metropolitan-level characteristics on asthma largely because of limited metropolitan variation in available data. Metropolitan-level residential segregation affects minority housing, and housing conditions are an important determinant of asthma. The All of Us project should collect asthma... more »

Voting

6 votes
Ideate
(@mpwhitmire)

AoU Research Priorities Use Cases

What social determinants & health/functional factors increase the risk of malnutrition for older adults living in the community?

It is important that the All of Us database includes a range of nutrition-related measures which are used to help identify malnutrition risk. Additional measures of malnutrition-related characteristics are important for malnutrition diagnosis. Validated screening tools such as the Malnutrition Screening Tool (MST) could be used regularly to collect this data, as well as linked surveys to capture demographic information... more »

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75 votes
Ideate

AoU Research Priorities Use Cases

Does "race" as self-identified by patients meaningfully correlate with DNA?

Ask participants to self-identify "race" as they would be asked on many organizational forms, such as employment, school, and insurance forms. Examine if DNA of participants correlates with their self-identified "race." My theory is "race" is a meaningless categorization of most people, but nevertheless people often use social categories without significant correlation with DNA. If true, then the All Of Us data could... more »

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10 votes
Ideate
(@fearnp)

AoU Research Priorities Use Cases

What if any are the differences in health outcomes for genetic versus self-reported demographics?

What if any are the differences in terms of cancer incidence and treatment outcomes for genetic demographics (biological sex, ethnicity) versus comparable self-reported demographics (gender, race, nationality)? The goal of this research would be to explore the relative contribution on disease, health, and outcome of genetically determined demographic characteristics versus personal, social or culturally determined demographic... more »

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11 votes
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