(@pradeepsuri1)

AoU Research Priorities Use Cases

Are there clinically meaningful subgroups of low back pain (LBP) defined by lifestyle, clinical features, and/or genomics?

LBP is the #1 cause of years lived with disability worldwide (GBD 2016), yet little is known about its underlying mechanisms. In standard clinical care, people with very different presentations of LBP are treated the same. Longitudinal survey items related to LBP, and data collection already planned by AoU (surveys + physical measurements + EHR + genomics) can be used to identify meaningful LBP subgroups that are connected... more »

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(@westrw)

AoU Research Priorities Use Cases

Which PAIN GENES/PATHWAYS are commonly expressed in patients with ARACHNOIDITIS or low back pain with radiculopathy

1. Identify patients with a diagnosis of arachnoiditis or low back pain with radiculopathy

2. Examine genetic variants, and gene expression and epigenetic status of respective genes

3. Determine if a genetic relationship among respective patient community

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