Endometriosis is a systemic condition with a heavy burden on patients. It is estimated that 10% of women in reproductive age have endometriosis, but its etiology is still unknown. While it is accepted that endometriosis is a heterogeneous condition, what the exact subtypes of the disease are is still an open question.
Showing 3 ideas for tag "sub-phenotype"
Heart failure (HF), though relatively common in U.S. adults, can be thought of as a syndrome with many subtypes that require different treatments. All of Us provides a rich platform on which to collect more data (e.g., novel biomarkers and imaging studies) on HF patients. This, coupled with AoU’s existing rich genomics, behavioral, and clinical data, can be analyzed to refine the phenotyping and sub-classification of... more »
Identify a cohort with a specific medical condition, intervention, and outcome and use heterogeneous patient measurements. Using a novel, soon-to-be-published machine learning platform that performs "X-rays" of cohorts, discover distinct sub-populations, their sub-phenotypes, and different outcome rates. The ability to discover distinct sub-populations characterized across many modalities would greatly advance the... more »