(@scd.pp)

AoU Research Priorities Use Cases

Study mechanisms of cardiac arrhythmias and sudden cardiac death for improvement of its prediction and prevention

Development of prediction and prevention of cardiac arrhythmias is necessary. Routine 12-lead 10-sec ECG is widely available and inexpensive. ECG can be also easily monitored via ECG patches. Study design: a prospective cohort. Routine 12-lead digital ECG at baseline, for measurement of electrophysiological phenomena. Outcomes: (1) genome; to study biology behind electrophysiological substrates. (2) cardiac arrhythmias... more »

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6 votes
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(@suddencardiacdeath)

AoU Research Priorities Use Cases

Reduce the burden of sudden cardiac death by identifying individuals who benefit the most from the implantable defibrillator.

The burden of sudden cardiac death remains high, accounting for over 350,000 deaths in the US annually. The implantable defibrillator remains the major primary prevention modality. However, in order for this important measure to stay sustainable from a health costs perspective, the criteria for selecting candidates most likely to benefit need to be improved significantly. It will be important to identify all use cases... more »

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35 votes
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(@rkchang)

AoU Research Priorities Use Cases

Electrocardiogram (ECG) and genomics in predicting coronary heart disease, MI, arrhythmia, stroke and sudden cardiac death

Electrocardiogram (ECG) is the most commonly used test to check on heart health and screen for heart disease. Medical standard 12-lead ECG holds a lot of information about the heart, which together with genomic data have the potential to predict which patients will develop coronary heart disease, myocardial infarction (MI), arrhythmia, stroke and sudden cardiac death. With 1 million people's ECG and genomic data, together... more »

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17 votes
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