(@hhenrylai)

AoU Research Priorities Use Cases

What are the biological and behavioral factors that predict mesh complications after sling for stress urinary incontinence?

Stress urinary incontinence (SUI) is prevalent among women, yet the standard of care treatment – midurethral mesh sling – can lead in devastating mesh complications (dyspareunia that precludes sex, chronic pelvic pain, infection). Using national data, we will identify biological (eg, genomics, vaginal & urinary microbiome, race, comorbidities, metabolic syndrome) and behavioral (eg, smoking, physical activity) factors... more »

Voting

2 votes
Ideate
(@abrsmith)

AoU Research Priorities Use Cases

Different types of physical activity are associated with an increase or decrease in the risk of urinary symptoms in older adults

Lower urinary tract symptoms (LUTS, eg incontinence, overactive bladder, slow urinary stream) negatively affect quality of life of many individuals as they age, yet some people never experience LUTS. Different types of physical activity (eg walking versus heavy lifting) may protect against or increase the risk of LUTS. We propose to identify people >65 years old, with and without LUTS, and identify how physical activities... more »

Voting

33 votes
Ideate
(@allison.polland)

AoU Research Priorities Use Cases

Does habitual holding of urine eventually lead to symptoms of urinary urgency?

Patients who present with urinary urgency often report that earlier in life they were able to hold their urine for long periods of time. Voiding diaries collected over time, perhaps yearly, could be used to answer this question. The results of this study could be used for patient counseling for prevention of urinary urgency and urge urinary incontinence.

Voting

14 votes
Ideate
(@jenna.norton)

AoU Research Priorities Use Cases

What characteristics define women with Urinary Incontinence who respond to midurethral sling surgery, versus those who don’t?

Midurethral sling surgery (MuSS) outcomes are inconsistent. We lack knowledge of outcome moderators. This study will identify a prospective subcohort of women aged 18+ with incident successful and unsuccessful MuSS. Hypothesized moderators of MuSS outcome spanning the social ecological model (e.g., urinary microbiome, comorbidities, BMI, physical activity, race, occupation, income) will be compared across those with successful... more »

Voting

20 votes
Ideate
(@jenna.norton)

AoU Research Priorities Use Cases

What characteristics define women with Urinary Incontinence who respond to midurethral sling surgery, versus those who don’t?

Midurethral sling surgery (MuSS) outcomes are inconsistent. We lack knowledge of outcome moderators. This study will identify a prospective subcohort of women aged 18+ with incident successful and unsuccessful MuSS. Hypothesized moderators of MuSS outcome spanning the social ecological model (e.g., urinary microbiome, comorbidities, BMI, physical activity, race, occupation, income) will be compared across those with successful... more »

Voting

10 votes
Ideate