Defining heightened sensitivity as an increased hazard ratio for an association between air pollution and a health outcome, identify subsets of the population based on molecular factors, e.g. genetic variants, hypermethylated regions, which are at increases risk of adverse cardiovascular or pulmonary events during high air pollution days.
I have no clue how I would study it to be completely honest... But I have horrible body odor and terrible bad breath because of Trimethylaminuria (tmau). It is caused by a deficiency of flavin monooxygenase 3 (FMO3) secondary to mutations in the FMO3 gene. Please help me and others with this problem.
The proposed study would identify microbial communities and metabolic profiles associated with stigmatized conditions such as idiopathic malodor or mental health. Working with systemic malodor/PATM community provides unprecedented opportunities to explore biomarkers of depression, social stress, diabetes, inflammatory diseases, dental, cardiovascular, and digestive health, exposure to antibiotics, lifestyle & dietary... more »
1) Collect the genetics of drug metabolizing enzymes from the genetic samples in the All Of Us study. 2) Describe the population genetics of these specific genes. How many people are normal (extensive metabolizers, EMs)? How many have other profiles? How many genes is the "average person" abnormal for? 3) By collecting data for "allergies" (some of which are intolerances, not true allergies) and medication reactions requiring... more »