Health-related quality of life (HRQOL) is a common metric for individual and population health and for comparing outcomes across health conditions. Utility-based HRQOL measures are used to estimate Quality-Adjusted Life Years for cost-effectiveness and other studies. Including utility-based HRQOL in regular AOU data collections (baseline onward) will support myriad statistical, modeling, and evaluation studies by combining... more »
AoU Research Priorities Use Cases
Below are the research questions others have already entered. IdeaScale is temporarily closed, but you can read what has been submitted so far. When re-opened, you can leave a comment or vote for the ideas you like. At that time, you'll also be able to submit your own idea.
When you are ready to submit your own idea after IdeaScale is re-opened, click the "Submit New Idea" button in the top right corner. Moderators from our team will review your submission and then add it to the rest of the submitted research questions.
To review the All of Us Research Program's Policy on Posting in IdeaScale, please click here.
To determine the barriers that prevent people from volunteering for medical research studies several questions need to be answered. The methods of advising people of studies for which they qualify need to be examined annually. The methods of reducing perceived risks for volunteering to participate in research should be examined. Successful methods of recruitment across the medical community need to be evaluated and... more »
Traditionally, occurrence of microvascular disease (retinopathy) has been used to define the glucose threshold by which diabetes should be defined. But these studies have come from mostly white/European/middle eastern populations. Do all ethnic groups have similar thresholds for diagnosis? Are certain diagnostic tests better for making the diagnosis of diabetes than others in select race/ethnic groups? The pathophysiology... more »
Research has shown that benefits of health behaviors such as diet, exercise, and stress depend not just on the behaviors themselves but on the mindsets people have about those behaviors (Crum, Achor & Salovey, 2013; Zahrt & Crum 2017; Turnwald, Boles & Crum 2017); however, large-scale databases have not yet included measures of mindset. The goal of this study is to use validated measures of exercise, stress and diet mindsets... more »
Half of all Americans are diagnosed with one or more chronic illnesses, like heart disease and cancer. Mindsets about these illnesses may have a profound impact on the diagnosis, progression, and treatment of these illnesses. This study aims to: (1) understand the distribution of mindsets held by a diverse group of both healthy and chronically ill Americans, and (2) identify relationships between these mindsets, biomarkers... more »
Patients, like many of the 11.2% of Americans with chronic pain, can feel that providers do not take their health concerns seriously. The goals of this research are: 1. identify factors (e.g., race, gender, SES) that affect perceptions of how seriously the healthcare system takes the concerns of patients across a variety of conditions (e.g., fibromyalgia, lupus) and, 2. test how these perceptions affect patient health... more »
Longitudinal narrative inquiry capturing diverse voices of study participants receiving genetic test results has the potential to fill gaps in the understanding of individual/family expectations; reactions; actions; and outcomes. Objectives: assess attitudes, literacy, perspectives about receiving genetic test results, implications of results for self/others, family communication pathways, and valued resources. Qualitative... more »
This study would compare those using conventional tampons to those using organic tampons or external menstrual products only and look at length of menstruation (number of days), pesticide metabolites, and pregnancy outcomes.
Peripheral artery disease (PAD) affects about 13% of the population over 50 years and it is an important cause of morbidity and mortality. The ankle brachial index (ABI) is an inexpensive and non-invasive test used to screen for PAD, and an abnormal value is associated with increased cardiovascular events. Adding the collection of serial ABIs to the All of US database will allow for numerous future studies aimed at defining... more »
This study would look at aspects of the home environment, including: cleaning products, address or block group for GIS mapping, proximity to roadways or certain agricultural or industrial facilities, pets, number of people living in the household, type of flooring, building structure, ventilation, type of heat, mold, and moisture level.
HOCL is currently used in hospitals as a wound care agent. Several promising research studies have been done to suggest this molecule can do more than we currently know. Now that it is readily available, trials on patients with vulvadynia and/or chronic yeast infections could be conducted to confirm its' healing properties for these specific conditions. It would be expected that patients would see noticeable symptom... more »